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Applications:
The
vacuum freeze drying is an advanced method for the material dewatering.
It freezes the moisture material in the low temperature and makes
the water inside sublimate directly in the vacuum condition.Then
it collects the sublimated vapor by means of the condensing way
so as to dewater and dry the material.
Being processed by the vacuum freeze drying,the physical,chemical
and biological states of the material are basically unchanged.The
volatile and nutritious contents in the material,which are easy
to be denatured in a warm condition,will be lost a little.When
the material is freezing dried,it will be formed into a porous
one and its volume be basically the same to that before drying.Therefore,the
processed material can be recovered quickly if being watered again,because
of its large contacting area.and it can be stored for a long period
in a sealed vessel.
The
vacuum freezing dryer can be widely used for the research and
production of various heat-sensitive biological products such
as the vaccine,biological product,medication,vegetable vacuum
packing,snake powder,turtle capsule and so on.
With the development of the biological,pharmaceutical,food and
health are product industries,the vacuum freezing dryer is a necessary
equipment in the research institutes and companies in such industries. |
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SIP |
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- Use overheat
pure steam(120C).
- Equipped
with cooling water jacket,after sterilizing,it can fast reduce
the temparature of the chest.
- Optional
pneumatic door lock,it locks automatically.
- Use import
sterilization filter to ensure the absolutely sterilized air
coming into equipment.
- The chest
and various kinds of container and tube are all wrapped with
import insulation layer to efficiently avoid from heat transmission.
- Can carry
out constant humidity control to the refrigeration humidity.
- Equipped
with water circulation pump capable to elliminate residual water
in sterilization layer.
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CIP
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- The high-pressure
clean thoroughly wash inner surface of the chest and condenser.
- Equipped
with large flow rate CIP pump.
Fixed wit
CIP tubing that automatically drains the residual water.
- Use rotary
and fixed nozzle with 360-degree spray.
- The hydraulic
system uses isolated retractable corrugated tube.
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Operation |
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- Square
or round shape chest(user may choose on of them).
- Horizontal
or vertical condenser.
- Integral
design can fully use space.
- Separate
design can make each component independent,easy to operate and
maintain.
- Working
temperature scope of condenser:-80C(when it is dry)~120C(when
in steam sterilizing).
- Pressure
scope of the chest:1Pa
- Use industrial
pressure container standard:
GB150-1998 series.
- Conform
to national vacuum equipment
standard:GB/T3163-3164
- GMP and
FDA relevant regulations
- Standard
of International Electrotechnical
Commission(IEC)
- China Electric
Equipment Standard(GB)
- The chest,lamellar
and condenser is made of AISI316L stainless steel.
- TIG welding
avoids gap that can not be coeaned.
- The welding
point of the tube is photographed with X-ray,with inspection
record and certificate of qualification.
- The roughness
of inner surface reaches R=<0.5,
- Leakage
rate of the system=<5*1/10²mbar I/s to ensure normal
and reliable running.
- There is
no dead corner in the chest,the connection of tube is simple
and reasonable,easy to clean.
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The
freeze drier uses the best refrigeration system to freeze the product
and condensate the steam produced ruring freeze-dryingprocedure.Freeze-drying
technology requirese the refrigeration system to keep a low temperature
status for a long period of time,therefore,the requirements to the
refrigeration system are very high.But the freeze drier of Shanghai
Yuan Dong Phamaeutical Machinery General Factory can easily help
you to reach your goal. |
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- Uses world
famous brand, e.g.Frascold, Danfoss,Copeland,Castel,Edwards,and
etc.
- The system
uses double stage half sealed piston compressor to reach first
class temperature reducing speed rate and the lowest temperature
in China.
- The system
power equipped is much greater than needed to efficientyly ensure
the refrigeration performance.
- Digital
and module design has a high pretection to ensure the system
to run normally and stably.
- The powerful
refrigeration system,liquid spray cooling system and other protection
installations keep to the best working temperature and high
system reliability.
- The sensitive
transducing system can provide alarm and protection in time
against abnormal running situation.
- Uses refrigerant
conforming to the world environment protection requiment,such
as HCFCR22 and HFCRA for choice.
- Special
synthetic lubricating oil can eliminate various kinds of problem
due to high temperature of normal mineral oil.
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The
vacuum system of the reeze drier provides a necessary pressure environment
to freeze drying procedure.Cooperating with condenser,It can reach
the vacuum level required by the freeze-drying procedure.To make
the system run stably under high vacumm situatin.the key point is
the performance of the vacuum pump,and the valve,seal and instrument
that cooperate with the pump. |
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- Standard
configuration,uses Edwards double stage oil sealing revolving
plate pump.
- Option:Edwards
pump.
- Equipped
with two vacuum probes,for measuring the vacuum level of freeze
drying chest and pump respectively.
- Option:condenser
type vacuum meter.
- There are
two methods for drying chest vacuum level control:
Drying chest vacuum level controls the opening and closing of
the air inlet valve,introduce the sterilized air from sterilized
room.
Drying chest vacuum level controls the opening degree of the
big butterfly valve to reach the purpose of controlling the
vacuum level.
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The drying chest and wate capturer valve,circulating pump,spotlight
and etc.of the freeze driver,like other components of the freeze
drier,like other components from other countries or from domestic
factories.
The above systems of the yuan Dong freeze drier have
the following |
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Characteristics: |
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- A couple-clamping
butterfly valve is equipped between the drying chest and water
capturer to keep a no leakage seal in both directions.
- Use labial
margin seal design to compensate the change of temperature and
pressure during operation.
- Eccentric
valve rod and eccentric butterfly valve eliminate the wear-out
of upper and lower ends of valve seat during frequent opening.
- May choose
electric or pneumatic driving device.
- Import
original electric driver can stepless adjust the opening sideness
of butterfly valve,control the vacuum level of the drying chest
to avoid from being polluted.
- Stainless
steel valve body and TEF elastic valve seat conform with GMP
specification.
- The drying
chest and water capturer are equipped with viewing glass.The
viewing glass can be equipped with spotlight to obtain clear
procedure monitoring.
- Shelf refrigerating
heating system uses Denmark Grundfos UPS circulation pump,Sweden
plate type heat exchanger.The size of the exchanger is small,this
reduces the heat conduction mediator and energy consumption,raises
the refrigeration efficiency.
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The
control system of the freeze drier provides a reliable whole procedure
control for the freeze driver.It has advanced functions of display,control,recording,printing
and alarming.
The control system characteristics:
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- The mains
air switch,transformer and AC contactor fixed in electric cabinet
are Siemens products.The electric cabinet is secured onmachine
frame. all machine pump motors are equipped with overheat protection,solenoid
valve and heating circuit are equipped with separate protection.
- The display
screen uses Mitsubishii touch screen,PLC programmable logic
controller,indicating light,sound-light alarming system,andetc.
- Temperature
measuring,pressure measuring,the compponents can work normally
under high temperature,ultra-low temperature and high vacuum
level with high reliability.
- The control
system can display the running status of alll components of
the whole system,and can store and process the operation information
and various date.It can provide procedure recording report of
whole freeze-drying process.It can set freeze-dryingcurve,monitor
each status in freeze-drying procedure.It can alarm on failure
or abnormal situation,provide cheching for maintenance,the operator
can set and modify data and step.
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