Product Overview

The LPGZL0.5 Pilot Industrial Vacuum Freeze Dryer Lyophilizer is a high-performance pilot-scale freeze drying system, designed and manufactured strictly in accordance with GMP standards. Built with 316L stainless steel, seamless chamber transitions, and advanced CIP (Cleaning-In-Place) system, it ensures hygienic, efficient, and reliable lyophilization. With a compact design and 0.5 m² shelf area, it is suitable for laboratories, R&D centers, and small batch production. Featuring optional SIP sterilization, precise vacuum control, and an intelligent PLC-based monitoring system, it provides stable performance, easy operation, and complete traceability of the freeze-drying process.

Features & Benefits

✅ Premium Construction – All product-contact parts are 316L stainless steel, surface roughness ≤0.5μm.

✅ Sanitary Design – Smooth chamber with no dead corners, easy cleaning and sterilization.

✅ CIP System – High-pressure water cleaning, 360° rotary nozzles, automatic drainage.

✅ Vacuum System – Standard double-stage oil-sealed pump;  optional ULVAC/Edwards vacuum pump.

✅ Accurate Monitoring – Dual vacuum probes for precise pressure readings.

✅ Flexible Vacuum Control – Supports both air inlet valve and butterfly valve control.

✅ Advanced Control System – PLC + touchscreen interface, data recording, freeze-drying curve setup, alarm system.

✅ High Reliability – Siemens electrical components, overheat and circuit protection.

✅ Temperature Range – Shelf temperature from -55°C to +70°C;  condenser reaches -75°C.

✅ Compact & Efficient – Small footprint, 5.5KW power consumption, only 730kg weight.

Product Details

Product Parameters

Product Application

• Pharmaceuticals – Lyophilization of injections, vaccines, enzymes, proteins, antibiotics, biological products.

• Biotechnology – Preservation of cultures, diagnostic kits, DNA/RNA materials.

• Food & Nutraceuticals – Freeze drying of coffee, herbal extracts, fruits, vegetables, and probiotics.

• Chemicals – Drying of heat-sensitive compounds, intermediates, and fine chemicals.

• CIP

1. The high-pressure water thoroughly wash inner surface of the chamber and condenser.

2. Equipped with large flow rate CIP pump.

3. Fixed with CIP tubing that automatically drains the residual water.

4. Use rotary and fixed nozzle with 360-degree spray.

5. The hydraulic system uses isolated retractable corrugated tube.

• Characteristics

1. Standard configuration, uses double stage oil sealing revolving plate pump.

2. Option: ULVAC or Edwards pump.

3. Equipped with two vacuum probes, for measuring the vacuum level of freeze drying chest and pump respectively. 

4. Option: condenser type vacuum meter.

5. There are two methods for drying chest vacuum level control:

5-1. Drying chamber vacuum level controls the opening and closing of the air inlet valve, introduces the sterilized air from sterilized room.

5-2. Drying  chamber vacuum level controls the opening degree of the big butterfly valve to reach the purpose of controlling the vacuum level.

• Control and optimum disposition

The control system of the freeze drier provides a reliable whole procedure control for the freeze drier. It has advanced functions of display, control, recording, printing and alarming. The control system has the following characteristics:

1. The main air switch, transformer and AC contactor fixed in electric cabinet are Siemens products. The electric cabinet is secured on machine frame. All machine pump motors are equipped with overheat protection, solenoid valve and heating circuit are equipped with separate protection.

2. The display screen uses touch screen, PLC programmable logic controller, indicating light, sound-light alarming system and etc.

3. Temperature measuring, pressure measuring, the components can work normally under high temperature, ultra-low temperature and high vacuum level with high reliability.

4. The control system can display the running status of all components of the whole system, and can store and process the operation information and various data. It can provide procedure recording report of whole freeze-drying process. It can set freeze-drying curve, monitor each status in freeze-drying procedure. It can alarm on failure or abnormal situation, provide checking for maintenance, the operator can set and modify data and steps.

FAQ

Q1: What is the shelf area of this pilot freeze dryer?
A1: The shelf area is 0.5 m² with 4+1 shelves.

Q2: What material is used for product-contact surfaces?
A2: All contact parts are made of 316L stainless steel with mirror-polished finish.

Q3: Does it support CIP/SIP?
A3: Yes, CIP (Cleaning-In-Place) is standard, and SIP (Steam-In-Place) is optional.

Q4: What industries use this freeze dryer?
A4: Pharmaceuticals, biotech labs, food/nutraceuticals, and chemical industries.

Q5: What is the condenser capacity?
A5: The condenser captures up to 10 kg of water, with a minimum temperature of -75°C.

Q6: How is the system controlled?
A6: It uses automatic + manual control, with PLC, touchscreen, real-time monitoring, and alarms.